Peritoneal mesothelioma is a rare and aggressive cancer that affects the lining of the abdomen, and it is primarily caused by exposure to asbestos. Due to the severity of the disease and its limited treatment options, there is a great need for clinical trials and research studies to find new treatments for peritoneal mesothelioma.
Currently, there are several clinical trials and research studies underway aimed at developing new treatments for peritoneal mesothelioma. One promising area of research is immunotherapy, which harnesses the body’s immune system to attack cancer cells. Other studies are exploring the use of targeted therapies that can specifically target cancer cells while leaving healthy cells unharmed.
One such clinical trial is investigating the use of a drug called pembrolizumab, which is an immunotherapy drug that works by blocking a protein called PD-1, which cancer cells use to evade the immune system. This clinical trial is exploring the use of pembrolizumab in combination with chemotherapy for patients with advanced peritoneal mesothelioma.
Another clinical trial is looking at the use of a drug called defactinib, which is a targeted therapy that blocks a protein called FAK that is important for cancer cell survival and growth. This trial is testing the safety and efficacy of defactinib in combination with chemotherapy for patients with mesothelioma.
In addition to clinical trials, there are also ongoing research studies aimed at understanding the biology of peritoneal mesothelioma and identifying potential targets for new treatments. For example, one recent study found that a protein called HSP90, which is involved in cancer cell growth and survival, may be a promising target for new therapies for peritoneal mesothelioma.
Overall, while the treatment options for peritoneal mesothelioma remain limited, ongoing clinical trials and research studies offer hope for new and effective treatments in the future. Patients with peritoneal mesothelioma should speak with their doctors about the availability of clinical trials and other research studies that may be appropriate for their individual situation.